Molecular characterization of the intestinal microbiota in patients with and without abdominal bloating

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Molecular characterization of the intestinal microbiota in patients with and without abdominal bloating.

Recent studies have demonstrated differences in the intestinal microbiota between patients with irritable bowel syndrome (IBS) and healthy controls (HC), suggesting a role for the intestinal microbiota in the pathogenesis of IBS. Alterations in the microbiota have also been implicated in the pathogenesis of abdominal bloating, a commonly reported symptom in IBS. We investigated the relationship...

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INTESTINAL MOTILITY Impaired reflex control of intestinal gas transit in patients with abdominal bloating

Background: Patients with abdominal bloating and distension exhibit impaired transit of intestinal gas which may lead to excessive gas retention and symptoms. Furthermore, we have previously shown that intestinal gas transit is normally accelerated by rectal distension. We hypothesise that in patients with functional bloating this modulatory mechanism fails and impairs gas transit. Methods: In ...

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Impaired reflex control of intestinal gas transit in patients with abdominal bloating.

BACKGROUND Patients with abdominal bloating and distension exhibit impaired transit of intestinal gas which may lead to excessive gas retention and symptoms. Furthermore, we have previously shown that intestinal gas transit is normally accelerated by rectal distension. We hypothesise that in patients with functional bloating this modulatory mechanism fails and impairs gas transit. METHODS In ...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology

سال: 2016

ISSN: 0193-1857,1522-1547

DOI: 10.1152/ajpgi.00044.2015